KISS1 over-expression suppresses metastasis of pancreatic adenocarcinoma in a xenograft mouse model
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چکیده
منابع مشابه
Calpain inhibitor calpeptin suppresses pancreatic cancer by disrupting cancer–stromal interactions in a mouse xenograft model
Desmoplasia contributes to the aggressive behavior of pancreatic cancer. However, recent clinical trials testing several antifibrotic agents on pancreatic cancer have not shown clear efficacy. Therefore, further investigation of desmoplasia-targeting antifibrotic agents by another mechanism is needed. Calpeptin, an inhibitor of calpains, suppressed fibroblast function and inhibited fibrosis. In...
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ژورنال
عنوان ژورنال: Clinical & Experimental Metastasis
سال: 2010
ISSN: 0262-0898,1573-7276
DOI: 10.1007/s10585-010-9349-5